Thiazolidinediones Linked to Risk for Osteoporotic Fracture

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Thiazolidinediones (TZDs), which are used to treat type 2 diabetes mellitus, are associated with a 1.3-fold elevation in risk for osteoporotic fracture compared with other antidiabetic medications, according to a report published online March 6 in Pharmacoepidemiology and Drug Safety.

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  • This study was supported by a grant from the European Calcified Tissue Society and by the Dutch Organisation of Scientific Research. The Department of Pharmacoepidemiology and Clinical Pharmacology, which employs Dr. Bazelier and 3 coauthors, has received unrestricted funding for pharmacoepidemiologic research from GlaxoSmithKline, Novo Nordisk, the private–public-funded Top Institute Pharma, the Dutch Medicines Evaluation Board and the Dutch Ministry of Health. Two coauthors also work for the General Practice Research Database in the United Kingdom.
  • Pharmacoepidemiol Drug Saf. Published online March 6, 2012.
    Share, medical news, author:Ricki Lewis, PhD
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